ʻO nā māka ʻaʻī pancreatic

ʻO nā huaelamu e haku ai i nā neoplasm malignant e ʻano nui loa, e hoʻopau ana i kā lākou mau mea ponoʻī a me nā ʻoihana capillary, a me ka wikiwiki ka hoʻokaʻawale ʻana, e hōʻoia ai i ka ulu ʻana o kahiʻano. No kēlā ʻano hana, pono lākou i ka nui o nā mea kanu, ka oxygen a me nā ikehu, a ma muli o nā hopena biochemical, ua hoʻokuʻu ʻia nā mea kūʻokoʻa no ka ulu ʻana i ka maʻi maʻi.

Ua kapa ʻia lākou i nā hōʻailona ʻalopelo, a i ʻole "mau hōʻailona" e pili ana i ka pathology cancer, ke ʻae nei lākou iā ʻoe e kānalua a hōʻoia paha i ka ʻike ʻana i ka maʻi ʻaʻi i kona wā mua, i ka mea maʻi ʻaʻohe ʻōmaʻomaʻi maʻi. Eia kekahi laʻana, he mau momona a he pūhui protein-carbonate hoʻi i ʻike ʻia i loko o ke koko venous i ka wā hōʻike.

Nā ʻano hua ʻōlelo ʻaila

ʻO nā ʻano āpau o ka maʻi pancreatic (pancreas) he mea pōʻino loa, me kahi hoʻomaikaʻi hikiʻole. ʻO ka helu ola o nā maʻi, ʻoiai ke kūpaʻa ʻana o ka mālama o ka mālama koʻikoʻi, he liʻiliʻi iki, i ka nui o nā hihia ke alakaʻi i ka hopena ʻoi aku ka hopena ma hope o nā mahina 6-12. No laila, he mea nui ka nānā mua ʻana o ka maʻi hōʻino.

ʻO kēlā me kēia māka laka he ʻōpiopio paʻuhū-paʻakikī

I kēia manawa, ua manaʻo ʻia nā mākaka maʻi pancreatic i manaʻo nui loa i ka hoʻolālā maʻi, ʻike ʻia i loko o ke koko, i ka nui o nā hihia, i ka wā e ʻike ʻia ana kahi neoplasm malignant i ke kino. I loko o kahi kanaka olakino, ke kuhikuhi nei ka nui o nā huaʻōlelo o kēia mau mea a i ʻole hemahema, no laila ke hōʻike aku nei ko lākou ʻike i ka neʻe ʻana o ka maʻi maʻi.

Hoʻohana ʻia nā māka ʻaʻelima ma lalo nei no ka nānā ʻana i nā diagnostics:

• ʻO ka CA-242 e hua ʻia e nā tumors ʻaʻole wale o ka pancreas, akā ʻo ka ʻōpū hoʻi; hoʻonui pū me ka pancreatitis a i ʻole gland cysts; ka loiloi o ka hopena o ka loiloi i hui pū ʻia me nā mākau ʻē aʻe.
• CA-125, hoʻonui ʻia me ke kanesa o ka pancreas, ate, rectum, ʻōpū.
• Hōʻike ʻia ʻo Tu M2-PK (ka maʻi pyruvate kinase) i kahi kikoʻī.
• ʻO AFP (alpha-fetoprotein), hōʻike i ke kano o ka pancreas, colon, ʻ liverpū.
• CA 72-4, e hoʻonui ai i loko o ke kaila benign a me nā keʻa o ka pancreas, a me ka maʻi pancreatitis a me nā maʻi.
• Hoʻokumu ʻia ʻo CA 19-9, e nā ʻāpana maʻi, ʻo ia ka "degenerated" epithelium o nā papa pancreatic. Hopu pū ʻia nō hoʻi i ke kano o ka pāʻai biliary a me nā ʻawaʻawa, me ka cirrhosis, pancreatitis, maʻi gallstone, cholecystitis.
• Manaʻo ʻia ka CA-50 ka māka kiko kikoʻī o ka ʻili āpau i loaʻa a me kahi kiʻekiʻe kiʻekiʻe o ka hilinaʻi hōʻoia i ka hiki ʻana o ke kano maʻi maʻi ma nā pancreas.

Loaʻa nā mākau maʻi maʻi pancreatic ʻē aʻe i nā waiwai diagnostic ʻokoʻa loa, ʻaʻole i hoʻokokoke ʻia ʻo 100%, ʻoiai ke ʻike ʻia ka CA 19-9 a i ʻole CA-50. No laila, he forcologist no ka nānā ʻana i ka maʻi maʻi e hoʻohana i ka ʻikepili pili i ka ʻike i loko o ke koko o ke kanaka maʻi o kekahi mau hōʻailona hōʻailona i ka manawa hoʻokahi. Akā ma kēia mau hihia, aia wale nō ma kahi o 70 pakeneka o nā maʻi āpau i loaʻa maoli i ka maʻi pancreatic "hiki ke ʻike" i kekahi ʻike maka i nā kikoʻī. Eia nō naʻe, ʻo kā lākou ʻike inoa ka ala hou loa a me ka hilinaʻi diagnostic.

Nā hōʻailona no ka hoʻoholo

No kēlā me kēia pūmua protein ma luna o ka papa inoa, ua hoʻoholo ʻia nā kapu kiʻekiʻe o ka helu, ka nui o ka mea e hiki ai ke hōʻike i ke ʻano o ke kaʻi maʻi ʻana, ʻaʻole wale nō i loko o ka pancreas, akā ma kekahi ʻaoʻao o ka digestive tract, i loko o ka ate, gall bladder. Hiki ke hoʻohana ʻia kahi hopena hōʻike maikaʻi wale nō no ka maʻi ka maʻi maʻi, akā no nā kumu ʻē aʻe. No ka laʻana, e nānā i ke ʻano o ke koʻi i ka wā e mālama ai.

Kūpono kekahi māka o ka hōʻeha ʻana i nā mea hōʻeha o ka maʻi a me nā hihia e hōʻeha nei i ka ʻeha o ka ʻōpū, ke kaumaha, ke hōʻemi ʻana i ka ʻili

Ma keʻano holoʻokoʻa, nā kūlana āpau i ka wā e pono ai e ʻike i kahi māka maʻi maʻi pancreatic i loko o ka mea maʻi, no ka hoʻoholo ʻana i kona ʻano kūʻauhau a me ka quantitative, hiki ke hōʻike ʻia e like me kēia:

• ka hele ʻana o nā ʻike pili i ka maʻi lapaʻau e hopohopo i ka maʻi kanesa pancreatic;
• ka heleʻana o nā cyst i hōʻikeʻia, pseudocysts, pankulopay pseudotumor;
• ka loiloi o ka ʻoiaʻiʻo o ka wehe ʻana i ke kaʻa holoʻokoʻa (inā paha i hoʻokaʻawale ʻia nā ʻāpana o ke kanesa);
• ka loiloi ikaika ʻana o ka hopena o ka chemotherapy a me ka radiation radiation;
• ka nohona ana i ke kūlana o kahi walaʻau paʻa;
• ke komo ʻana i nā metastases i nā ʻokoʻa ʻē aʻe;
• ʻike maka ʻana o ka maʻi pancreatic;
• hopohopo mua i ka maʻi ʻaʻai o ka gastrointestinal tract;
• ka hopena maʻi ʻana o ka neoplasms malignant a me benign neoplasms.

Hiki ke ʻike ʻia mai ka papa inoa o nā hōʻike, ʻo ka hapanui o lākou e pili ana i nā hihia o nā maʻi maʻi i hoʻopaʻa ʻia. No kahi laʻana, koi ʻia nā ʻōlelo hoʻohālikelike mākaʻikaʻi ʻia no ka nānā ʻana i ka maʻi cancer i ka wā conservative therapy a ma hope o ka hoʻomaʻamaʻa ʻana. Eia nō naʻe, ʻo ka ʻike ʻana i ka māka ʻana ke kīpoki nui loa i ka wā nui e pono ai ke hōʻoia i ka hele ʻana a i ʻole hemahema o ka neoplasm malignant, a ma ka manawa mua, i ka manawa e hōʻike ʻole nei ka maʻi i kahi hoʻopiʻi a ʻaʻohe hōʻailona lapaʻau o ka patology. Ma kēia e pili ana i kēia hana, e hoʻokomo i ka noiʻi screening no nā mākau maʻi ʻoi i ka papa inoa o nā hoʻokolohua pono ʻia e mālama ʻia i ka wā o ka hoʻokolokolo ʻo ʻana i nā ʻāpana āpau o ka lehulehu.

I ka hapanui o nā hihia, ʻaʻole naʻe, e ʻimi nā maʻi i ke kōkua i ka wā i hōʻike ʻia ai ke kiʻi kuʻuna pili maʻi pancreatic lesions. Pane paha lākou i ka hōʻeha o ka ʻōpū a i ʻole ka ulu ʻana i ka hōʻeha ma ke ʻano o ke kāʻei, ka hoʻonui nui ʻana o ka ʻili a me nā membous mucous, a me ka nalowale ʻole o ke kaumaha o ke kino.

Lawe ʻia ke koko Venous no ke aʻo ʻana ma hope o ka hoʻomākaukau ʻana o ka mea maʻi.

Ma ia mau kūlana, e loaʻa ana nā hoʻokolohua no ka māka ʻana me ka huakaʻi ʻole, a hoʻokahi noiʻi, ʻoiai hoʻi i ka hopena maikaʻi, ʻaʻole lawa no ka maʻi definitive maʻi pancreatic cancer. Manaʻo ʻia kekahi mau hōʻike ʻana a me ka loaʻa ʻana o nā hopena maikaʻi i loko o ka hoʻopaʻa ʻana ʻo 3 mau ʻanoʻano ʻoʻehā o nā hōʻailona maʻi.

Nā ʻimi noiʻi a me ka ʻikepili

Pono ke koko Venous e ʻike i nā māka maʻi maʻi, e lawe ʻia ana mai ka ulnar vein. I ka manawa like, pono e hōʻike ʻia nā mea hōʻike a pau ma ke kikowaena like ʻole a me ka hoʻohana ʻana i nā ʻano like noiʻi like, a laila e loaʻa ai ka hilinaʻi kiʻekiʻe loa o nā hopena.

Ma mua o ke kuʻi koko ʻana, ka mea i lawe ʻia i ke kakahiaka a ma mua o ka ʻai ʻana, pono ʻia kahi hoʻomākaukau liʻiliʻi a maʻalahi hoʻi o kekahi kanaka.

MRI ʻO pancreatic

Aia ia mau hana penei:

• i loko o 8 mau hola ma mua o ka noiʻi hiki ʻole ke ʻai i ka meaʻai;
• ka lā ma mua o ke ʻano o ka hoʻoili ʻana, ʻaʻole hiki iā ʻoe ke ʻai i ka momona, ka pākī, ka ʻili, ka puʻu kīkī, me ka wai o ka wai ʻai, a me nā kīwaha ikaika;
• no 2 mau lā ʻaʻole hiki iā ʻoe ke inu i ka ʻawa ʻawa.
• no 2 lā hiki iā ʻoe ke hoʻohana i nā lāʻau lapaʻau inā ʻaʻole koʻikoʻi.

Ke ʻimi ʻia nei ka ʻike ʻana i ka hapa nui o ka poʻe hana ma mua o 1 lā. I nā pilikia pilikia, ua mākaukau ka hopena i kekahi mau hola.

ʻO kekahi mau mea like nā loea biochemical i hoʻoili ʻia e nā ʻona maʻamau i loko o nā ʻokoʻa o nā kino o loko a i ʻole nā ​​ala i ʻike ʻole ʻia e ke ʻano o kahi nano. No laila, no kēlā me kēia māka ʻaila, ua hoʻoholo ʻia nā pākuʻina nui, kahi e hoʻopiha ai i kona paʻa ʻole a me nā mea liʻiliʻi, ʻae ʻia i ke koko o ka mea maʻi.

ʻAʻole like nā hualoaʻa no nā māka maʻi i ka wā i hoʻāʻo ʻia ai i loko o nā mea hana like ʻole. ʻO kēia ma muli o nā hiʻohiʻona o nā mea hana, me nā hiʻohiʻona ʻenehana, me ke ʻano hana kumu. No laila, he mea nui loa ka mālamaʻana i nā ʻike kuʻina o nā mea e pili ana i ka ʻike.

No ka laʻana, ka huaʻōlelo o ka helu helu i lalo no ka mau māka maʻi:

• CA 19-9: mai 0 a 40 IU / ml;
• CA-50: ʻaʻole ʻoi aku ma mua o 225 U / ml;
• ACE: 5 a 10 IU / ml;
• CA-242: ʻaʻole iʻoi aku ma mua o 30 IU / ml.

ʻO ka wehe ʻana i nā meaʻai momona a me ka momona ma mua o ka loiloi e loaʻa kahi hopena i ka hopena.

Inā loaʻa ka mea maʻi oncologist i nā hopena like, a ma ka nui o nā hihia ke hiki iā ia ke maopopo i ka mea maʻi e ola ana a ʻaʻohe ona maʻi hōʻeha i ka maʻi o ka pancreas a me nā ʻāpana hana ʻē aʻe. Inā ua hoʻomaka ʻia ka palia ma hope, a laila e kuhikuhi kēia mau kuhikuhi i ka "hōʻemi o ka nui o ke kaʻina o ka hoʻoulu, ka hopena kiʻekiʻe o ka hopena, a me ka nalo o nā metastases. Eia nō naʻe, ʻo ka noi ʻana ʻana no nā māka maʻi ʻāpiki ʻaʻole hiki ke hoʻoponopono i ka hoʻomaka ʻana o ka hoʻololi o nā ʻōnaehana olakino i loko o nā maʻi kanesa, ʻo ia hoʻi, ka laʻina mua o ka maʻi.

Ke piʻi nei i nā waiwai maʻamau ke koʻikoʻi a makaʻu loa, no ka mea e ʻae ʻia me ka hopena kiʻekiʻe e hōʻike ai i ka loaʻa ʻana o ke kanesa. Eia kekahi, ʻoi aku ka nui o ka nui o ka nui o nā markers, ʻoi aku ka nui o ka lāʻau a me ka mea hiki ke kūkulu i ka metastases.

E hoʻonui ka nui o ka diagnostic i kahi liʻiliʻi wale nō o ka neʻe ʻana, ʻo ka hiki ʻana i nā pono maʻamau o nā māka pākahi. ʻO kēia no ka loaʻaʻana o kekahi poʻe i ka genetically hikiʻole ke synthesizing i kekahi mau māka, no ka laʻana, CA 19-9. No laila, ʻo kā lākou mau "waiwai", e kū'ē i ka ulu ʻana o kekahi nui o nā ʻōmaʻomanaʻo, ʻaʻole e hōʻole i ka heleʻana o kahi neoplasm malignant.

Lawe aʻeha ka maʻi pancreatic i kēlā me kēia makahiki. ʻO kāna maʻi mua, me ka hoʻohana ʻana i kahi loiloi o nā māka maʻi ʻoi loa, he mea nui loa a kōkua i ka hoʻonui ʻana i ke ola o nā mea maʻi.