Thioctic acid he mea ia e like me ka vitamin, e like me ka endogenous antioxidant. ʻO ka pauna dosage ka lāʻau lapaʻau e koho ai i ka mālama ʻana i ka hana o ka endothelioneural (ka hopena o ke kau ʻana a me ke ʻano o ke kōpaʻa ma muli o ke kahe ʻana o ka hoʻokahe koko ma muli o nā hanana endothelial vascular) a me ke kaumaha oxidative.
Tagu inoa
Lipoic acid, alpha lipoic acid, thioctacid he mau huaʻōlelo no ka thioctic acid.
I ka ʻōlelo Pelekane, kapa ʻia ka inoa o Thioctic acid. I Latin - Acidum thiocticum (genus Acidi thioctici). Heʻokoʻa paha ka inoa kālepa (Oktolipen, Berlition 600, etc.).
Thioctic acid he mea ia e like me ka vitamin, e like me ka endogenous antioxidant.
ATX
ʻO ka waihona ATX ʻo A16AX01.
E hoʻokuʻu i nā palapala a me ka ʻano
Loaʻa iā:
- ʻO nā pōpō
- ka hopena no ka ʻōkuhi, 1 ml nona ka 25 mg o ka acid-lipoic acid;
- hoʻokūkū i ka hopena no ka hoʻopuʻe.
Loaʻa ka Thioctacid i ke ʻano o nā papa kuʻi.
Nā Palaki
Loaʻa ka Thioctacid i ke ʻano o nā papa pani i loko o kahi kaona o 200 a me 600 mg o ka mea ikaika.
ʻĀpono
I ke ʻano o kahi paura, ʻaʻole i hoʻohana ʻia ke ʻano o nā mea lapaʻau, no ka mea soluble wale nō i ka ethanol.
Ka hana lāʻau lapaʻau
ʻO ka lilo ma antioxidant kūlohelohe, thioctacid pale i ka hana o ka nappa kumu kappa-bi ma muli o nā radical manuahi. ʻO ka hōʻino ʻana i kona hoʻoponopono pili i nā maʻi o ka autoimmune, cell cell distort a me ka apoptosis (make) o nā pūpū.
ʻO ka hopena nosological no kāna mau waiwai:
- komo i ka hopena o ka decarboxylation o nā waika alpha-keto - e hōʻoia ana i ka hoʻololi ʻana i ka ikehu a me ka pale ʻana o DKA;
- hiki ke hoʻohaʻahaʻa i ka pae o nā momona momona, cholesterol;
- antioxidant - ka hoʻopili ʻana i nā polikino maikaʻi, nā hāpū pale, hoʻihoʻi i ka glutathione;
- ka papa o ke kāpili ʻana o ka nitric oxide e nā ʻāpana ʻāpana - pale a me ka hoʻomaha ʻana o ka phlebopathy;
- radioprotective.
Ma ka hana ʻana i ka endothelium o nā kīʻaha koko, ka lipoic (thioctic) waikiki e hōʻemi i ka hōʻeha ʻana i ko lākou papale i loko, e hōʻemi ana i ka lumen, fragility a me ka hopena o nā kīnā koko.
Mahalo i kēia mau waiwai o ka thioctacide, ua loaʻa ka lāʻau i ka hopena multifaceted i ke kino:
- hoʻōla i ka holo koko neural;
- pale i ka hoʻokae ʻana ʻana o NO synthetase, ka mea e pale ai i ka pōʻino o ischemic i nā kihi o ka pūnaehana;
- Hoʻonui i ka hana o nā mea hoʻonāukiu o ke aʻalolo;
- hoʻoponopono i ka hana o glutathione;
- hoʻoweliweli ka pōʻino i nā membrane cell.
ʻO ka hopena o ka hana o ka hana a ke kuʻi:
- ka normalization o ka cholesterol;
- ke emi ʻana o ka pale ʻana i ka insulin;
- hoʻonui hoʻonui kaliki;
- ka pale ʻana o ka Isela pancreatic e hana ana i ka insulin;
- ka hoʻemi ʻana o nā pae lipid, e wehewehe i ka hopena maikaʻi o ka mālamaʻana i ka momona;
- ka pale ʻana o ka cell edema ma muli o ka hōʻiliʻili ʻana o ka sorbitol i loko o lākou;
- ka hoʻomaikaʻi ʻana i nā mea elastic a me ka microcirculation o nā moku koko;
- ka hōʻemi ʻana o nā mea anti-inflammatory i ka plasma koko;
- ka hoʻomaikaʻi ʻana i ka hana detoxification o ka ate, ka hana ʻana o nā waikaʻi bile a pale i nā membrane o ke kō o ke kino mai ka ʻeha ʻole.
Ka hana i ka endothelium o nā pili koko, ka lipoic (thioctic) acid ka mea e hōʻemi ai i ka hōʻeha ʻana i ko lākou papa i loko, e hoʻoneʻe ana i ka lumen, brittleness a me ka hopena o nā kīʻaha koko, nā hana maʻi.
Hoʻopuka maʻalahi ka waihona i ka pale koko-lolo, kahi e hoʻoholo ai i kona pono i ka mālama ʻana o ka encephalopathy a me nā maʻi ʻōnaehana o ka naʻau: Alzheimer a me Parkinson.
Lapaʻau lāʻau
A lawe pono ʻia, hoʻihoʻi piha ʻia ka lāʻau i loko o ka digestive tract. Co-hoʻokele o kahi lāʻau ʻai me ka meaʻai e hōʻemi ana i kona nalo ʻia. ʻO ka hana Peak (Cmax) o ka lāʻau lapaʻau ka mālama ʻia o kahi hapa o hoʻokahi hola a i hoʻokahi hola ma hope o ka hoʻokele ʻana. I loko o ka puʻuwai, ka biotransformation o ka alpha lipoic acid i ka wā o ka hele mua ʻana ma o nā paia o ka pūpū, nā puʻupuʻu, nā lewa, e hoʻonui ana i ka bioavailability o ka waiwai a hiki i ka 30-60%.
A lawe pono ʻia, hoʻihoʻi piha ʻia ka lāʻau i loko o ka digestive tract.
ʻO kāna Vp (ka palena lahilahi) ma kahi o 450 ml / kg, e hōʻike ana i ka laula o ka lāʻau lapaʻau i loko o nā kiko o ke kino. ʻO ka hapalua ola (T1 / 2), a i ʻole ka nalowale o ka hana o 50%, o ka lipoic acid he 20-50 mau minuke, aia ma muli o ke kāʻili ʻana o nā huahana o nā hoʻololi o ka waiwai e kū ai i loko o ka palaleka ma o nā keiki. ʻO ka helu o ka hoʻomaʻemaʻe ʻana i ke kaila o ke koko (Cl plasma) mai ka lāʻau lapaʻau he 10-15 ml / min.
Ka mea e pono ai
Hoʻohana ʻia ka Thioctacid i ka mālamaʻana i nā maʻi i hoʻoiho ʻia e ka maʻi oxidative, hyperinsulinemia, kūlia insulin, endothelial dysfunction. Hoʻohana ʻia ma ka mālamaʻana o:
- ʻO nā maʻi me ka maʻi maʻi a me nā hoʻopiʻi ʻana, e like me:
- polyneuropathy diabetic;
- encephalopathy maʻi maʻi;
- maʻi pūpū momona ma nā mea maʻi me ka pale ʻana i ka insulin;
- retinopathy diabetic;
- cardiovascular autonomic neuropathy;
- ʻopi momona
- Hōʻailona o ka Polycystic ovary syndrome i nā wahine.
- ʻO nā maʻi o ka naʻau i hoʻomoʻi ʻia me ka inu wai hoʻohālike, nā metala kaumaha, nā mea ʻala ʻili; ka hoʻolauna ʻana o kahi ʻaopio viral (hepatitis C maʻi maʻamau, B).
- ʻO ka pancreatitis Alakika.
- Hoʻokomo ʻia ka Rheumatoid.
ʻO ka mea waiwai, me ka hiki ke hoʻoponopono pono i ka paʻakai a me ka momona o ka metabolism, i hoʻohana ʻia ma ke ʻano he ʻāpana o ka meaʻai e hoʻemi i ke kaumaha a mālama i ka momona.
A ma ka cosmetology, hoʻāla ʻia ka acid no:
- hoʻopau i ka mumū;
- ka pale mai nā hopena o nā mea maikaʻi waho e hoʻokauwale ai i nā ʻili;
- wehewehe, pale UV;
- kiko kiko;
- glycation pale pale - ke kaʻina o "gluing" collagen fibers me glucose;
- kauʻike.
Hoʻonui ka mea i ka hopena ma ka ʻili a me ke kino o ka waiola D, ascorbic acid a me tocopherol.
I nā huahana kosmetic, ʻaʻole iʻoi aku ma mua o 10% lipoic acid e like me ka EU Regulation. Hōʻike ʻia ko lākou hoʻohana ʻana i nā wāhine me ka ʻili o ke kino, ka hyperpigmentation, kahiʻano o ka nāʻeha, nā huhū. Hoʻohana pū kekahi ʻia me nā thioctacid inā e ʻaʻa ka ʻili, me nā pā a hoʻonui ʻia a me nā huehue.
Nā Hoʻohui
No ka mea ka hoʻohuihui lipoleic ma ka nui o ka mea e pono ai e hiki ke endogenously synthesized ma ke kino o ke kanaka, hana maoli ʻole ia he contraindications i ke kumu. ʻO ka contraindication nui ka hypersensitivity i ka hana. E hoʻohana i ka lāʻau lapaʻau me ka makaʻala me:
- hapai a lactation;
- ʻO nā makahiki ahonui 6 mau makahiki.
ʻO ka contraindication nui ka hypersensitivity i ka hana.
Ma muli o ka nele o ke ʻike ma ka hoʻohana ʻana i ka lāʻau lapaʻau ma nā mea maʻi o kēia mau pūʻulu a me ka nele o kahi nui o nā hopena palekana.
I ka lāʻau lapaʻau pil, pono ke noʻonoʻo ʻia ka hiki ʻana o ka lactose e like me ka mea hoʻopihapiha. ʻO ke kumu o ia mau ʻano, ua contraindicated i loko o nā mea maʻi me ka malabsorption - hoʻonolo lactose intolerance.
Pehea e lawe ai i ka wai thioctic
Hoʻomaka ka Therapy me ka hoʻohana ʻana i ka lāʻau thioctic ma o ka hana intravenous a infusion hoʻokō i ka lāʻau. Ke hoʻomau ʻia ke kūlana, kuhikuhi ʻia ka hana mālama me nā papa.
I ka hana ʻana o ka hopena o ka infusion mai ka neʻe ʻana i ka ampoules, e hoʻoheheʻe ʻia ko lākou ʻike me ka hopena saline - ʻĀhaʻi NaCl.
No ka ʻae ʻana a ka waha (ma ka waha), ua ukali ʻia kēia mau ʻōlelo ʻana:
- lawe ʻia ma mua o ka papa i hoʻokahi lā;
- mai kolo, holoi, inu nui i ka wai;
- ma hope o ka hapalua hola e pono ai ʻoe i ka pāʻina kakahiaka;
- ka aiau kela la i kela la i keia manawa aole oi aku i ka 600 mg o thioctacide;
- ʻo ka hana o ka mālama ʻana he 3 mau mahina, e like me nā hōʻike ʻana, hiki ke hoʻonui ʻia ka lōʻihi o ka lāʻau.
Hoʻomaka ka Therapy me ka hoʻohana ʻana i ka lāʻau thioctic e ka hui intravenous o kahi māke.
Hoʻolālā ʻia me ka papa ʻaina ma hope o ka papa he mau hebedoma 2-4 o ka hana o ka hana intravenous a infusion paha i ka lāʻau.
Intravenously, mālama ʻia ka lāʻau lapaʻau e pale aku i nā hopena ʻaoʻao. Ka hoʻoponopono ʻia ʻana i ka dropper i ka hoʻoluhi hoʻoluhi haʻahaʻa. ʻO ka nui ka 300-600 mg.
Hoʻohana ʻia hoʻi ka Thioctic acid no ka hoʻokele intramuscular. No ka hōʻalo ʻana i nā hopena ʻino, ʻaʻole ia e kuhi ʻia e hoʻoiho i nā ʻōmole o ka 2 ml ma kahi hoʻokahi.
Thioctic acid i ka hoʻoikaika kino
I ke bodybuilding, hoʻoikaika ikaika a me nā haʻuki hoʻokūkū, hoʻohana ʻia ka thioctacid e hōʻemi i ke kaumaha oxidative ma hope o ka hoʻoikaika kino nui. ʻO ka hiki i ka hōʻemi i ka hana glucose a hoʻokaʻawale iā ia i nā mea ikehu kiʻekiʻe ka mea nui: a ʻo kēia waiwai o ka lāʻau lapaʻau e kōkua i ka hāʻawi ʻana i ka ikehu i nā ʻili kino a loaʻa i ka hopena kiʻekiʻe loa mai ke aʻo. Eia kekahi, hoʻonui ka acid i ka thermogenesis, kōkua i ka hōʻemi ʻana i nā momona momona i nā wahi pilikia, no laila ua kuhikuhi ʻia ʻaʻole wale nō i ka mea haʻuki, akā no ka hoʻolilo ʻana i ke kaumaha.
I ke bodybuilding, hoʻoikaika ikaika a me nā haʻuki hoʻokūkū, hoʻohana ʻia ka thioctacid e hōʻemi i ke kaumaha oxidative ma hope o ka hoʻoikaika kino nui.
Hōʻike ʻia nā mea pāʻani ʻōpio i kahi hapa o 50 mg 3-4 mau manawa i ka lā ma kahi o kahi hola ma hope o ka pāʻina. Me ka hoʻomaʻamaʻa koʻikoʻi, hoʻonui ka nui o ka lāʻau lapaʻau i 300-600 mg i kēlā me kēia lā.
Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi
Ma ka maʻi mellitus, hoʻomaka ka lāʻau lapaʻau e hoʻomoʻa ma ka makua (i ke kāʻei i ka ʻōpū). Hoʻomoe ʻia ke kūlohelohe i 100-250 mg o ka 0.9% sodium chloride a ma kahi o 600 mg e lawelawe ʻia ka dropwise intravenously no nā lā 15. Hoʻohana ʻia ka lāʻau lapaʻau i loko o nā alikaʻe o 5 mau lā me nā lā 2 mau lā ma waena o lākou. I ka huina, 15 ampoules e hoʻohana ʻia no ke ʻano o ka mālama ʻana.
Ma hope o ka hoʻopau ʻana i ke ʻano maʻi injection, lawe ʻia ka mea maʻi i nā papa thioctacid, 1 pc. i kahi lā ma mua o ka ʻaina kakahiaka.
Ma ka maʻi mellitus, hoʻomaka ka lāʻau lapaʻau e hoʻomoʻa ma ka makua (i ke kāʻei i ka ʻōpū).
ʻO ka hoʻololi ʻana i ka glucose a hoʻōla i ka hana ʻana o kou iho ponoʻī e koi ai i ka hoʻoponopono ʻana o ka insulin a me nā lāʻau hoʻohaʻahaʻa i ka lāʻau. I nā hoʻopiʻi koʻikoʻi, hiki ke mālama ʻia ka hopena o ka mālama iā 3-5 mau mahina.
Nā hopena hopena
Hoʻomaopopo nā hopena maikaʻi i ka hihia 1 i kēlā me kēia 10,000 mau maʻi. Hōʻike ʻia i ke ʻano o:
- pilikia kino kino;
- hypoglycemia;
- me ka hana waha, nā maʻi dyspeptic, ka ʻōpū ʻōpio, nā ʻōpū epigastric e hiki ai;
- me ka iv, kaʻaila, ka piʻi ʻana o ke kahe o ke koko a me ke kumu intracranial, ʻike ʻia he ʻelua pihi, apnea, thrombosis, a me ka hemorrhage.
Manalo nā hōʻailona inā hōʻemi ʻia ka hopena a ma hope paha o ka pau ʻana o ka hana.
Nā ʻōlelo kikoʻī
ʻO nā maʻi me ka maʻi maʻi e kiaʻi pinepine i nā pae glucose. He photosensitive loa nā hāmeʻe i hoʻomākaukau ʻia, no laila hoʻohana koke ʻia lākou ma hope o ka hoʻoilo ʻana a pale ʻia paha me kahi pale kukui.
Hoʻolaha ka waipuna
ʻAʻole kūpono ia ka lāʻau lapaʻau me ka waiʻona, no ka mea hoʻemi ka maikaʻi o ka ethanol i ka hopena o ka hoʻolaha.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
ʻAʻole ia e pili kūpono i ka helu o ka hopena neuromuscular, akā, hiki i nā hōʻike kino ke hōʻike i ke akahele ʻana i ka wā o ka ʻoihana.
Hoʻohana i ka wā hāpai a me ka lactation
Hoʻomaopopo ʻia ka kuhikuhi ʻana i kahi lāʻau lapaʻau i ka wā hana o ka wā hiki ke loaʻa ka loaʻa o ka hoʻomaʻamaʻa ʻana ma o ka loaʻa ʻana o nā hanana hiki. I ka hihia ke pono ke mālama ʻia i ka wā e ʻokiʻoki ai, pono e hoʻokaʻawale i ke keiki i ka hānai hana.
Loaʻa ke kuhikuhi i kahi lāʻau lapaʻau i ka wā o ka wā gestational inā loaʻa paha ka loaʻa o ka mālama lapaʻau i nā hanana kūpono paha.
Ke koho ʻana i ka wai thioctic i nā keiki
ʻAʻole ʻōlelo nā kauoha no ka hoʻohana ʻana i ka lāʻau lapaʻau i kona hoʻohana ʻana i nā keiki nona ka makahiki ma lalo o 6 mau makahiki. Eia naʻe, e like me nā hōʻike, hiki ke kuhikuhi ʻia ka lāʻau i ka nui o:
- 0,012 g 2-3 mau lā i kahi lā no nā keiki ma lalo o 7 mau makahiki;
- 0,012-0.024 g 2-3 mau lā i kahi keiki no nā keiki o 7 mau makahiki.
Ke keu
ʻO ka liʻiliʻi o kahi overdose he liʻiliʻi, akā naʻe me ka nānā ʻana o kekahi a i ʻole hōʻino i ke protocol hoʻokele, hiki i kēia:
- lie kanikela
- ninaki a me ka luaʻi.
I kahi hihia o ka hoʻohālikelike, lawe ʻia ka hana e nānā i ka pani ʻana i nā hōʻailona.
Me kahi overdose o ka lālani, loaʻa ke poʻo.
Hoʻopili pū me nā lāʻau ʻē aʻe
ʻAʻole kūpono ka Acid i ka:
- Hoʻolaha ka Ringer a me nā mea hana ʻē aʻe e loaʻa ana ka calcium a me ka magnesium;
- kaʻenehana lāʻau;
- ethanol.
Hoʻonui ka lāʻau lapaʻau i ka hopena o nā insulin a me nā mea hoʻonā waha hypoglycemic waha.
Nā kuʻina
ʻO nā hōʻiliʻili o ka Acidum thiocticum nā lāʻau lapaʻau:
- ʻĀpana lepe;
- Berlition;
- Kauhaiʻili;
- Thiogamma;
- Oktolipen;
- Lipoic acid, kahi inoa maʻamau he vitamin N;
- Lipothioxone;
- Neuroleipone;
- Polokika.
Waihue huaʻōlelo waiho nā huaʻōlelo
Ma ke kumu.
Hiki iaʻu ke kūʻai me ke kī ʻole
ʻAʻohe.
ʻO ke kumu kūʻai o ka mika thioctic
Wahi a ka mea hana a me ke ʻano o ka hoʻokuʻu ʻana, he ʻano like ke kumukūʻai o ka lāʻau lapaʻau mai 40 (50 papa) a 2976 (100 mau papa) rubles. ʻO Thioctacid 600 i nā nui ampou e uku 1,539 mau rubles. no ka pahee. Ma Ukraine, ua piʻi ke kumukūʻai ma waena o 92 i 292 UAH.
Nā kūlana mālama
Kāleka B - E mālama i kahi kūmaʻomaʻo a heʻele.
Hoʻokuʻu wale ʻia ka lāʻau lapaʻau inā he lāʻau lapaʻau ka lāʻau lapaʻau.
ʻO ka lā kau
3 mau makahiki
Nā Huaʻōlelo Thioctic Acid
ʻAʻole lōʻihi ka lāʻau i kahi hoʻopaʻapaʻa i waena o nā mea hoʻohana a me nā loea. A me nā hiʻohiʻona o nā hiʻohiʻona o kēia wā me ka liʻiliʻi o nā hopena ʻona e alakaʻi i nā loiloi maikaʻi.
Kauka
ʻO Elena Sergeevna, ʻoihana lapaʻau, ʻo Kiev: "He maʻi maʻi wau a ua ʻike i ka hopena o ka waika thioctic, no laila, me ka noʻonoʻo maʻalahi, ke kau nei wau i ka Thioctacid BV i nā maʻi."
ʻO Inga Olegovna, endocrinologist, Kostroma: "Ma ka hana o ke kauka, he mea nui ia i ka ʻike o ka hopena a me ka palekana o ka lāʻau lapaʻau. Ua hoʻokau pinepine wau i ka hopena o ka hopena me ka lāʻau lapaʻau Thioctacid BV e like me ka haʻi ʻia."
ʻO nā maʻi maʻi
ʻO Mirra, he 45 mau makahiki, ʻo Krivoy Rog: "ʻEono mau mahina i hala aku nei, ua hoʻomaka wau e ʻike i ka palupalu i koʻu mau manamana lima a me nā lima. Ua ʻōlelo ke kauka, he kumu maʻi pākī ke kumu, a ua kuhikuhi aku i kahi papa papa o Thioctacid BV. Ua inu wale wau i ka hapalua, a ua hoʻomaikaʻi maikaʻi koʻu olakino."
ʻOksana, 31 makahiki, ʻo Odessa: "ʻO ka ʻōlelo aʻo e hōʻike ana he hiki i ka maʻi pākaʻi, akā ʻaʻole naʻe ka hopena i ka lāʻau lapaʻau me nā moʻo maʻi maʻi, ʻoiai iaʻu he maʻi alakine me ka ʻike."
ʻO Anna, 40 makahiki, ʻo Kazan: "Ma ka manawa o ka maʻi maʻi, ua nui ka pilikia o ka pōkole. Ua mālama wau i ka lāʻau lapaʻau no nā mahina he nui aku. Akā, ʻo ka mea inu wau i nā lāʻau lapaʻau he nui ʻē aʻe, ʻaʻohe ona hopena, ʻoiai ʻo ke kaumaha ua emi iki me ka ʻole o kahi mea make. "