Hoʻomau mau ʻia ka lāʻau lapaʻau maʻamau no ka maʻi maʻamau o ka maʻi maʻamau ma luna o ka lāʻau lapaʻau ʻana a me ka hoʻonohonoho kūikawā o nā ʻano kino. ʻO ka laʻana ʻo Diamerid i hōʻike ʻia no ka hōʻole ʻana o kēia mau hana.
Hoʻohana ʻia ka hoʻohana ʻana i ia ʻano lāʻau lapaʻau me ke kauka e komo nei, nāna i kuhikuhi i ka lāʻau lapaʻau ma luna o ke kiʻi maʻamau o ka maʻi o ka mea maʻi, ka puʻuwale o ka maʻi.
Pono ka papa therapeutic e koho pono ʻia i nā inika i koho pono ʻia e pale aku i nā hōʻike hewa ʻole o kahi lāʻau lapaʻau e like me ka diamerid.
ʻO ke ʻano o ka mālama lāʻau
I kēia mau lā, hoʻohana nā lāʻau lapaʻau hou i kekahi o nā pūʻulu o nā lāʻau lapaʻau e mālama ai i ka maʻi type 2. ʻO nā pahuhopu nui e pono e hoʻokō ma muli o ka hoʻohana ʻana i nā lāʻau lapaʻau e pili ana:
- ka hoʻoweliweli ʻana o ka hoʻāla haukaʻi insulin
- hoʻemi i ka insensitivity insulin o nā cellꓼ
- ka hoʻoleiʻana i ka hoʻohuihui glucose ma ka palalolo ʻana i kona kaomi ʻana i loko o ke koko mai ka ʻāpana aku
- ka hoʻoponopono ʻana i ka ala e hoʻāhewa ʻia ai i ka hopena o nā hoʻohālikelike lipid i ke koko.
E like me ke kānāwai, hoʻomaka nā lāʻau lapaʻau me ka neʻe ʻana o kekahi lāʻau lapaʻau; inā ʻaʻole pono, he lāʻau lapaʻau o nā hopena hui ʻole a i ʻole me nā inikini insulin e hiki ke kuhikuhi.
ʻO nā hui nui o nā lāʻau e hoʻohana ʻia ai e mālama i ka maʻi diabetes mellitus type 2:
- Nā lāʻau lapaʻau e pili ana i ka sulfonylurea. ʻO kā lākou mea kōkua nui, ʻo ka hoʻomanawanui maikaʻi o nā lāʻau lapaʻau i nā mea maʻi he nui. Ma kā lākou hana, hoʻemi ʻia lākou i ka pale ʻana i ka insulin a hoʻoulu i ka mea huna o ka hormone ma o nā papa pancreatic.
- Me nā kumuhana mai ka hui biguanide i hoʻohui ʻia i ka māhele metformin. ʻO ia ka hopena o ka metformin i kōkua i ka hōʻemi o ka huna hona, e hoʻopilikia i ka hana maʻamau o fez, a hoʻomaikaʻi i ka profil lipid. Hiki i ke koho hewa hewa ke alakaʻi i nā hopena ʻaoʻao he nui.
- Nā ʻōwili
- Hoʻomoe ka mākaukau e pili ana i ka deria e thiazolidinone e hōʻemi i ke kō koko koko a hoʻomaikaʻi i ka maikaʻi o ka ʻōlelo lipid.
ʻO ka hoʻohui ʻia ʻo Alpha-glucosidase a i ʻole nā peptidyl peptides 4 kahi i kapa ʻia nō he lāʻau lā; ua loaʻa iā lākou kahi hopena maikaʻi i ka hoʻopau ʻana o ka hyperglycemia a hoʻonui i ka naʻau o nā ʻāpana beta pancreatic i glucose.
ʻO nā waiwai nui o ka pharmacological o ka lāʻau
ʻO Diameride kahi lāʻau lapaʻau mai ka pūʻulu o nā kolu o ka wā o ka sulfonylureas. Hoʻohana pinepine ia e mālama i nā ʻano maʻi mellitus type 2, inā ʻaʻole i lawe ʻia mai ka hopena maikaʻi o ka lāʻau a me ka hana kino.
Loaʻa ka lāʻau lapaʻau i nā palapala papa i nā ʻano like ʻole - hoʻokahi, ʻelua, ʻekolu a ʻehā paha mau milligram o ke ʻano ikaika me nā mea hou i ka mana. ʻO ka hana koʻikoʻi o ka lāʻau lapaʻau ka glimepiride.
Hoʻokumu ʻia nā waiwai pharmacological nui o ka lāʻau lapaʻau.
- hoʻonui i ka ʻike ʻana o nā ʻoli i ka insulin.
- hoʻoikaika ikaika i ka pani ʻana o nā pā paʻakai, ma muli o ke kahe o ka intracellular o ka pākani hoʻonui a hoʻōla ʻia ka huna ʻana i ka insulin.
- mahalo i ka pae lipid pae.
- kōkua e ho'ēmi i ka platelet aggregation.
Eia kekahi, ʻo ka hoʻohana ʻana i nā papa e hoʻonui i ka hopena o ka insulin i ka heʻe ʻana o ka glucose e nā kōpili peripheral.
Hoʻohana pinepine ʻia ka lāʻau lapaʻau i ka hui pū ʻana i hui pū me nā lāʻau lapaʻau e pili ana i ka metformin (hoʻomaikaʻi i ka hoʻokolohua metabolic) a i ʻole ka hoʻoponopono ʻana o ka insulin.
He nui nā loiloi o nā mea maʻi e hoʻohana ai i kēia lāʻau lapaʻau e hōʻike i ka hoʻomanawanui a me ke kūpono o ka lāʻau lapaʻau.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻO nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana i ka lāʻau lapaʻau e haʻi pono ka hoʻomaka ʻana o ka lāʻau e hana me nā haʻahaʻa loa o ka lāʻau. Pēlā, e hoʻolako ʻia ka mana metabolic pono.
I ka wā o ka lawe ʻana i ka lāʻau lapaʻau, pono ke nānā pono i ka mea maʻi i ka pae o ka glucose i loko o ke koko, me ka hōʻikeʻana i ka hemoglobin glycosylated.
ʻO ke koho ʻana i kahi huahana lāʻau lapaʻau, me ke koho ʻana i nā ʻokoʻa kūpono, e hana ʻia ana e ke kauka komo ʻana. I kēia hihia, ʻaʻole pāpā ʻia ka lāʻau lapaʻau ponoʻī.
ʻO ka pololei o ka lawe ʻana i nā papa e pili ana i kēia mau ʻōlelo aʻoaʻo:
- Ma nā hana mua o ka mālama ʻana, ʻo ka nui loa ka ʻimi ʻia ʻana o ka lāʻau lapaʻau hoʻokahi milligram o ke ʻano ikaika i hoʻokahi manawa i ka lā. Ma hope o hoʻokahi a ʻelua paha mau pule, inā e kū mai ka pono, e hoʻonui ʻia ke ka palena o kēlā me kēia lā.
- ʻAʻole e oi aku ka lōʻihi o ka ʻāpono o ka hoʻohana ʻana i ka lāʻau lapaʻau ma mua o ʻewalu milligrams o ka lālani, ke hoʻolako ʻia nei ka nui o ka nui o nā pulu he ʻokoʻa, i kēlā me kēia mau lā a hiki i ka lā ʻumikumamāhā
- I kēlā mau maʻi nā mana āpau o ke kō o ka koko kōkuhi i hoʻoponopono maikaʻi ʻia, ʻo ka hopena o ka lāʻau i hōʻea i ka wā e lawe ai mai ka hoʻokahi a ʻehā milligrams o ka lāʻau. I kēia mau lā, aia kekahi helu liʻiliʻi o nā poʻe e pono e hoʻonui i kēia mau dosages i ʻewalu milligrams o ka lāʻau.
Manaʻo ʻia e lawe i ka lāʻau lapaʻau, e hahai ana i nā ʻōlelo āpau a ke kauka komo. Hoʻonohonoho ka mea lapaʻau i ka manawa a me ka nui o ka hoʻokomo ʻana, ma muli o ke ʻano o ke kanaka maʻi, hana a me ka pae o ka hoʻoikaika kino. Ma ke kānāwai, hoʻokau ʻia ka hoʻohana ʻana i ka lāʻau i hoʻokahi manawa ma ka lā ma mua o ka pāʻina nui (no ka laʻana, ma ke kakahiaka ma mua o ka ʻaina kakahiaka). ʻO ka mua ka hana maʻa ka ʻaina maʻamau a piha i ka ʻaina (ʻaina awakea, ʻaina pāʻina), inā ua lawe ʻia ka lāʻau lapaʻau. Eia kekahi, pono e halihali ma ka noʻonoʻo, inā, no kekahi kumu, ua nalowale ka pōpoki, ʻaʻohe pono e hoʻonui i kona ʻano ma ka hopena hou.
Aia aia nā kūlana e hoʻoponopono ai ke kauka i ka palena o ka lāʻau. Hoʻoholo ʻia ka hoʻoponopono ʻana inā loaʻa ka lilo o ka mea kaumaha o ka mea maʻi, aia nā loli i ka nohona o ka mea maʻi - ka nui a me ka maikaʻi o ka meaʻai, ka nui o ka hana kino, he nui ka hoʻonui ʻana o ka hyp- a i ka hyperglycemia ma muli o kekahi mau kumu ʻē aʻe.
He aha nā contraindications no ka hoʻohana ʻana?
ʻOiai he papa inoa inoa nui o nā hōʻino maikaʻi o ka lāʻau, pono ia e noʻonoʻo i nā ʻano like ʻole o nā hiʻohiʻona maikaʻi e hiki mai ana ma hope o kona hoʻohana.
ʻO ka mea mua, pono ia e mālama pono i ka papa inoa o nā papa i hoʻohoka ʻole ʻia me ka Diomexide. I waena o nā contraindications nui e pili ana i kēia mau ʻano:
Ka mālama ʻana o ka maʻi mellitus o ka maʻi mua, a ma ke ʻano o ka nānā ʻana i ka ketoocytosis maʻi maʻi a i ʻole ke ʻano o kahi maʻi maʻi maʻi maʻi i ka mea maʻi.
- ka hōʻike ʻana o ka haemogemia ma kahi maʻi,
- i ke alo o nā ala ākea
- hopohopo ʻia ka maʻi ʻōpio a ʻehā paha e ulu ai,
- intolerance a hypersensitivity paha i hoʻokahi a hapa paha o ka lāʻau lapaʻau,
- i ka heleʻana o ka lactose intolerance aiʻole lactase nele.
I kēia lā, ʻaʻole lawa ka ʻike e pili ana i ka hana a kēia lāʻau lapaʻau i ka mālama ʻana i ka maʻi diabetes i nā keiki. No laila, ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau no nā mea maʻi (a hiki i ka ʻumikumamāwalu mau makahiki). Eia kekahi, ʻo nā contraindications e lawe i ka lāʻau lapaʻau i nā kaikamāhine a me nā wahine i ka wā o ka hoʻoulu ʻana.
Me ka nui o ka makaʻala, ʻōlelo ʻia kahi lāʻau lapaʻau inā inā he nui o ka hopena o ka hypoglycemia, inā he mau kumu e pono ai i ka mea maʻi e neʻe i ka inikini o ka insulin ma hope o ka hōʻeha o ka maʻi, ke ʻano he maʻi o ka ʻano o ka hoʻoneʻe ʻana.
He aha nā hopena maikaʻi ʻole mai ka hoʻohana ʻana i ka lāʻau lapaʻau e hiki mai paha?
Ma muli o ke koho pono ʻole o ka make ʻana o ka lāʻau, ʻaʻole hoʻokae ʻole i nā ʻōlelo manaʻo a ke kauka hele ʻana i nā ʻano maʻi like ʻole.
ʻO kekahi o nā hopena hopena maʻamau he hoʻonui nui loa a me ka hooulu ʻana o ka hypoglycemia i kahi manawa lōʻihi. ʻO nā hōʻailona nui e hele pū ana i kēia ʻano maʻi:
- māhuahua mau momona a me ke ʻano mau ʻana o ka pōloli,
- nā kuʻeha koʻikoʻi
- ninaki a me ka luaʻi
- ka ʻike mau ʻana o ka luhi a me ka nāwaliwali o ke kino,
- huhū
- hiki ʻole i ka hoʻokū
- paʻakikī ka hanu
- ʻeha a palupalu,
- hoʻonui i ke koko.
I ka hoʻomaka ʻana o ka lāʻau hiki ke hele pū me ka ʻike ʻole ʻia o ka ʻike. He wā leʻa kēia ʻano a hoʻokuʻu ʻia nona iho no kahi wā.
Eia kekahi, ʻike nā manaʻo maikaʻi ʻole a me nā hopena ʻaoʻao:
- Nui nā ʻano maʻi o ka ʻeha gastrointestinal. ʻO ka ʻeha ma ka ʻōpū, hiki paha i ke ʻano ke hele a maʻi.
- Hōʻaha ka makemake i ke akepaʻa, ka hoʻomohala ʻana o ka hepatitis, jaundice a i ʻole cholestasis.
- Mai ka pūnaehana holoweliweli, ma nā hihia līkī, thrombocytopenia, ua hōʻike ʻia ka leukopenia a i ʻole ka pancytopenia.
- Hiki ke hōʻeha ʻia nā ʻōnaehana o ke ʻano, ka mea i hōʻike pinepine ʻia ma ke ʻano o nā ʻano ʻano maʻi āpau - urticaria, hōʻeha o ka ʻili a i ʻole paha.
ʻO kahi overdose o ka lāʻau lapaʻau ka hoʻonāukiuki ʻana i kahi hōʻeha o ka hypoglycemia koʻikoʻi i ka mellitus maʻi diabetes, hiki ke hala i hoʻokahi a i ʻekolu mau lā.
Hiki i kahi mea lapaʻau ke hoʻololi pū i kahi huahana me nā waiwai like?
ʻO ka lāʻau lāʻau he lāʻau lapaʻau, maʻalahi ia e komo ai i loko o nā lāʻau lapaʻau o ke kūlanakauhale. Hoʻololi kona kumukūʻai mai 170 a 600 mau rubles, e pili ana i ka dosis, ka wahi o ke kūʻai ʻana a me ka ʻoihana mea hana. Hōʻike nā loiloi o nā mea kūʻai aku e pili pū ana kēia lāʻau lapaʻau me nā hiʻohiʻona maʻamau o "ke kumu kūʻai". Aia nā kūlana i ka wā e noʻonoʻo ai i ka loli ʻana i kahi lāʻau lapaʻau a loaʻa kahi hoʻohālikelike kūpono.
I kēia lā, ua hāʻawi ka mākeke huahana lapaʻau hou i kahi koho ākea ākea o nā lāʻau lapaʻau like ʻole, aia ma kā lākou hui pū ʻana he mau analogitions pololei a Diamerid, a i nā mea like paha ona. Pono e hoʻomaopopo ʻia he hiki ke loaʻa nā hōʻola a nā inoa like ʻole, e hoʻopuka ʻia e nā hui ʻē aʻe, akā he mau mea like like me nā ʻano like ʻole. I ka huli ʻana, he like nā ʻenemi like me nā huahana pharmacodynamic like ʻole, akā ʻokoʻa kā lākou hui i ke huahana mua (no ka laʻana, nā papa Diabeton MV).
Aia nā analogues o Diamerid, ma waena o ia mea i makemake nui ʻia ʻo Amaryl, Glemaz, Glimepiride
ʻO Amaryl M kahi papa papa i loaʻa i nā ʻano like ʻole. Loaʻa ia mau hiʻohiʻona a me nā hōʻailona no ka hoʻohana. ʻO nā hiʻohiʻona o kēia lāʻau lapaʻau ke hiki ʻole i kekahi mau wahi o ka moku a i ke kumukūʻai kiʻekiʻe. Hiki ke kumukūʻai kumukūʻai mai 300 a 1000 rubles i kēlā me kēia pā (30 mau papa), e pili ana i ka dosage a me ka ʻoihana hoʻoneʻe.
Glemaz - nā papa i loaʻa i kahi maʻa o ʻehā milligrams o ka hana ikaika. Aia ka helu i ka pālima he kanakolu, ʻo ke kumukūʻai mai nā 325 a 865 mau rubles.
ʻO Glimepiride - kahi mea i hoʻohālikelike i ka lāʻau Diamerid. ʻO ka mea nui o ka hana like me kāna haʻahaʻa haʻahaʻa - mai ka 140 a 390 rubles.
He aha nā mea e hoʻohana ai i nā loea hypoglycemic e haʻi i ka mea loea i ka wikiō ma kēia ʻatikala.
